Mission:

The Imaging Core enables comprehensive data acquisition on brain structure and function at different spatial and temporal resolutions using our advanced optical imaging equipment.

Technology:

The Imaging Core provides the highest level of microscope equipment in the country. Observations of fixed brains, cultured cells, and even cells in the living mouse brain can be examined with various spatio-temporal resolutions ranging from submicron to whole brains.

Core Manager

Satoru Kondo
Project Associate Professor

Equipment explanation / reservation

Confocal microscope Nikon A1R
Confocal microscope Nikon A1R

It is an inverted type confocal laser microscope system. This microscope has a large FOV size of 25 and is equipped with a resonant scanner and laser unit LU-N4 (405, 488, 561 and 640 nm), and GaAsP detector. They enable to obtain images with high-speed and high-sensitivity. In addition, culture system (made by Tokai Hit) is also provided, and long-time live cell imaging is possible.

Pre order
Two photon microscope Nikon A1RMP2
Two photon microscope Nikon A1RMP2

It is an upright type multiphoton laser microscope system. High sensitivity and high quality images can be acquired with the GaAsP NDD unit. By using piezo elements to drive the objective lens in the Z-axis direction, it is possible to take 3D images at high speed. The femtosecond pulse laser can simultaneously use two laser lines with a variable wavelength of 700-1300 nm and a fixed wavelength of 1040 nm, and is suitable for long-wavelength dye and multicolor imaging.

Pre order
Virtual reality system PHENOSYS Jet Ball VR system
Virtual reality system PHENOSYS Jet Ball VR system

Virtual Reality (VR) systems can be used with the mouse to investigate brain function during behavioral tasks. You can examine the basic mechanisms of animal navigation, recognition, learning, or memory combined with two-photon and wide-field microscopes.

Pre order
Patch Clamp system [Patch clamp amplifier]Sutter Instruments IPA,[Manipulator]Sutter Instruments TRIO-245
Patch Clamp system [Patch clamp amplifier]Sutter Instruments IPA,[Manipulator]Sutter Instruments TRIO-245

The patch clamp amplifier supports dual recording. In addition, the manipulator can be driven in 3 axis directions + diagonal direction. We are preparing for in vivo patch clamps, so you need to prepare by yourself for performing in vitro experiments such as slice patches.

Pre order
All in one microscope KEYENCE BZ-700
All in one microscope KEYENCE BZ-700

It is a fluorescence microscope that does not require a dark room. With the sectioning function, you can obtain clear images without fluorescent blur with easy operation. In addition, high resolution wide field of view image can be taken at high speed by image joint function.

Pre order
Light sheet microscope RAPID
Light sheet microscope RAPID

Rapid-Scope is a custom-designed light-sheet fluorescence microscope (LSFM) with mesoscopic magnitude (0.5X-2X) to explore a volumetric sample by less-invasive optical slicing. The cleared brain sample is dipped in the oil and illuminated by spatially-uniform thin light-sheet which provides a three-dimensionally isotropic resolution and covers a wide area of visualization.

Pre order

List of scheduled events

Past event list

Past events are here

Usage Application Form

Carry-in laboratory equipment application form

Terms of Use

Rules of the microscope room usage

Important Notice Regarding the Observation of Fixed Samples

Rules for bringing animals to Imaging Core

Microbiological monitoring items